Invited Speakers
Nicolas G. Bazan, MD, PhDDirector, Neuroscience Center of Excellence
LSU Health Sciences Center
New Orleans, LA
Email: nbazan@lsuhsc.edu
Early protective responses to injury and neurodegeneration in brain, nerves and retina mediated by docosanoids
Andreas Billich, PhD
Novartis Research Institute Vienna
Wein, Austria
Email: andreas.billich@novartis.com
Sphingolipid metabolizing enzymes as novel therapeutic targets
Wen-Chang Chang, PhD
Department of Pharmacology
College of Medicine
National Cheng Kung University
Tainan, Taiwan
Email: wcchang@mail.ncku.edu.tw
Functional role of the acetylation/deacetylation of Sp1 in gene regulation
Yong Q. Chen, PhD
Wake Forest University
School of Medicine
Winston-Salem, NC
Email: yqchen@wfubmc.edu
Modification of cancer genetic risk by essential fatty acids
Jerold Chun, MD, PhD
Department of Molecular Biology
Helen L. Dorris Child and Adolescent Neuropsychiatric Disorder Institute
The Scripps Research Institute
La Jolla, CA
Email: jchun@scripps.edu
New physiological roles for lysophospholipid signaling
Samuel David, MD
Professor
Department of Neurology and Neurosurgery
McGill University
Montreal, Quebec, Canada
Email: samuel.david@mcgill.ca
Differential roles for members of the phospholipase A2 family in
neurological disorders
Edward A. Dennis, PhD
Department of Chemistry and Biochemistry & Department of Pharmacology
School of Medicine
University of California, San Diego
La Jolla, CA
Email: edennis@ucsd.edu
Profiling Inflammatory Mediators Initiated by Phospholipase A2 Through Eicosanoid Lipidomics
Vincenzo Di Marzo, PhD
Research Director
Istituto di Chimica Biomolecolare
Consiglio Nazionale delle Ricerche
Pozzuoli, Italy
Email: vdimarzo@icmib.na.cnr.it
Endocannabinoids and bioactive fatty acid amides in cancer and inflammation: an update
Wolfgang Dubiel, PhD
Division of Molecular Biology, Department of Surgery, Charité
University of Berlin
Berlin, Germany
Email: wolfgang.dubiel@charite.de
The COP9 signalosome regulates the ubiquitin- and proteasome-dependent degradation of COX-2
Thomas Eling, PhD
Senior Investigator
National Institute of Environmental Health Sciences
National Institutes of Health
Research Triangle Park, NC
Email: eling@niehs.nih.gov
Changes in gene expression by Cox inhibitors and cancer prevention
Edward Goetzl, MD
Prof. of Medicine and Immunology
University of California Medical Center
San Francisco, CA
Email: edward.goetzl@ucsf.edu
Control of T Cell-Mediated Immunity and Autoimmunity by the S1P-S1P1 Axis
Jesper Z. Haeggstrom, MD, PhD
Department of Medical Biochemistry and Biophysics
Karolinska Institutet
Stockholm, Sweden
Email: jesper.haeggstrom@mbb.ki.se
Crystal structure and mechanism of human leukotriene C4 synthase - an
integral membrane protein in allergic inflammation and immune regulation
Yusuf A. Hannun, MD
Ralph F. Hirschmann Professor & Chairman
Department of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, SC
Email: hannun@musc.edu
Role of neutral sphingomyelinase in cytokine responses
Kenneth V. Honn, PhD
Department of Radiation Oncology & Pathology
Wayne State Univeristy School of Medicine
Detroit, MI
Email: k.v.honn@wayne.edu
12-Lipoxygenase and the regulation of prostate cancer angiogenesis under normoxic and hypoxic conditions
Mariana Nikolova-Karakashian, PhD
Associate Professor
Department of Physiology
University of Kentucky College of Medicine
Lexington, KY
Email: mnikolo@uky.edu
Role of Hepatic Neutral Sphingomyelinase in Aging and Inflammation
Toshihiko Kawamori, MD, PhD, MIAC
Medical University of South Carolina
Pathology & Laboratory Medicine
Charleston, SC
Email: Kawamori@musc.edu
Role of the Sphingosine Kinase 1/Sphingosine-1-Phosphate pathway in
colon carcinogenesis. Is this pathway a more potent target for chemoprevention?
Steve Kridel, PhD
Department of Cancer Biology
Wake Forest University
School of Medicine
Winston-Salem, NC
Email: skridel@wfubmc.edu
The role of endogenous fatty acid synthesis in tumor cells
Robert Langenbach, PhD
Senior Investigator
National Institute of Environmental Health Sciences
National Institutes of Health
Research Triangle Park, NC
Email: langenb1@niehs.nih.gov
The prostaglandin E2 receptor, EP2, mediates signaling pathways that contribute to mouse skin tumor development
Norbert Leitinger, PhD
Department of Pharmacology
Cardiovascular Research Center
University of Virginia
Charlottesville, VA
Email: nl2q@virginia.edu
Oxidized phospholipids and their role in inflammation
Lawrence J. Marnett, PhD
Professor of Biochemistry and Chemistry
Director Vanderbilt Institute of Chemical Biology
Vanderbilt University School of Medicine
Nashville, TN
Email: larry.marnett@vanderbilt.edu
Cyclooxygenase-2 Targeted Imaging of Cancer
Jason Morrow, MD
Director of the Research Center for Pharmacology & Drug Toxicology
Chief, Division of Clinical Pharmacology
Vanderbilt University Medical Center
Nashville, TN
Email: jason.marrow@vanderbilt.edu
The isoprostanes as both pro- and anti-inflammatory mediators of oxidant stress in humans
Santosh Nigam MD PhD DSc(h.c.)
Head, Eicosanoid & Lipid Research Division
and Centre for Exp.Gynecology & Breast Research
Univ.-Klinikum Benjamin Franklin
Free University Berlin
Berlin /Germany
Email: santosh.nigam@charite.de
3-Hydroxyoxylipins upregulate PPARγ via Krüppel-like factor 13 (KLF13) in
HPV16-infected epithelial cells: fine tuning of the p53 gene promoter binding to NFkB sequence
Lina Obeid, MD
Boyle Professor of Medicine
Departments of Medicine, Biochemistry and Molecular Biology
Associate Director of Research Program, Center on Aging
Medical University of South Carolina
Charleston, SC
Email: obeidl@musc.edu
Bioactive sphingolipids in inflammation and cancer
Besim Ogretmen, PhD
Associate Professor
Department of Biochemistry and Molecular Biology
Medical University of South Carolina
Charleston, SC
Email: ogretmen@musc.edu
Roles of Bioactive Sphingolipids in Cancer Pathogenesis and Therapy
Pal Pacher, M.D., Ph.D., F.A.P.S., F.A.H.A
Chief, Section on Oxidative Stress Tissue Injury,
Laboratory of Physiological Studies, NIAAA/National Institutes of Health
Bethesda, MD
Email: pacher@mail.nih.gov
Role of CB2 cannabinoid receptors in endothelial inflammatory response: implications for ischemia-reperfusion injury, atherosclerosis and cardiovascular aging
John Parks, PhD
Department of Pathology Lipid Sciences
Wake Forest University
School of Medicine
Winston-Salem, NC
Email: jparks@wfubmc.edu
n-3 fatty acids, inflammation, and cardiovascular disease
Eugene Podrez, PhD
Dept of Molecular Cardiology
Cleveland Clinic Foundation
Cleveland, OH
Email: podreze@ccf.org
Oxidized phospholipids, CD36 and platelet hyper-reactivity as a mechanism of atherothrombosis
Hugh Rosen, MD, PhD
Professor of Immunology
Chair, Committee for Advanced Human Therapeutics
The Scripps Research Institute
La Jolla, CA
Email: hrosen@scripps.edu
Barrier regulation by S1P
Daniel W. Rosenberg, Ph.D.
Professor of Medicine
Investigator, Center for Molecular Medicine
Co-Director, Colon Cancer Prevention Program
UCONN Health Center
Farmington, CT
Altered Arachidonic Acid Balance and Colon Cancer
Robert G. Salomon, PhD
Department of Chemistry
Case Western Reserve University
Cleveland, OH
Email: Robert.Salomon@case.edu
Oxidatively Truncated Phospholipids: Formation and Protein Adduction
Charles N. Serhan, PhD
Director, Center Experimental Therapeutics and Reperfusion Injury
Brigham and Women's Hospital
Chairman Department of Oral Medicine, Infection and Immunity
The Simon Gelman Professor. Anaesthesia (Biochemistry & Molecular Pharmacology)
Harvard Medical School and Harvard School of Dental Medicine
Boston, MA
Email: cnserhan@zeus.bwh.harvard.edu
Mechanisms in Resolution of Acute Inflammation
Takao Shimizu, MD, Ph.
Professor and Chairman
Department of Biochemistry and Molecular Biology
The University of Tokyo
Tokyo, Japan
Email: tshimizu@m.u-tokyo.ac.jp
Cytosolic phospholipase A2 and lysophospholipid acyltransferases
William L. Smith, PhD
Chair, Biological Chemistry
University of Michigan
Ann Arbor, MI
Email: smithww@umich.edu
The 19 Amino Acid Instability Sequence Near the C-terminus of COX-2, COX-2 Suicide Inactivation and COX-2 Degradation
Dr. Gabor Tigyi, Ph.D
Department of Physiology
University of Tennessee Health Science Center Memphis
Memphis, TN
Email: gtigyi@physio1.utmem.edu
Exploring novel therapeutic targets for lysophospholipids
Natsuo Ueda, MD, PhD
Department of Biochemistry
Kagawa University School of Medicine
Kagawa, Japan
Email: nueda@med.kagawa-u.ac.jp
Enzymes involved in the formation of anandamide and related amide compounds
Kikuko Watanabe, PhD
Division of Life Science
University of East Asia
Yamaguchi, Japan
Email: watanabe@toua-u.ac.jp
A study of physiological role of mPGE synthase-2
Darryl C. Zeldin, MD
Senior Investigator
National Institute of Environmental Health Sciences
National Institutes of Health
Research Triangle Park, NC
Email: zeldin@niehs.nih.gov
Cytochrome P450 Metabolites and Cardiovascular Disease